Added: Jamael Wheeler - Date: 31.07.2021 07:57 - Views: 47523 - Clicks: 8443
Mechanisms underlying the associations of high levels of physical activity PA and adherence to the Mediterranean diet MedDiet with a better inflammatory profile remain unclear. Our objective was to assess the mediating role of changes in body mass index BMI and waist circumference WCas markers of body fat in the association of changes in PA and adherence to the MedDiet, with changes in the inflammatory profile. An inflammatory score was calculated, based on 8 blood biomarkers: high-sensitivity C-reactive protein, interleukin 6, interleukin 8, interleukin 18, monocyte chemo-attractant protein-1, C-peptide, leptin, and regulated on activation, normal T-cell—expressed and secreted chemokine.
Linear regression models were fitted according to the Baron and Kenny framework for mediation analysis. In older adults at high cardiovascular risk, increasing PA levels and adherence to a MedDiet during 1 year were associated with a lower inflammatory score, which was partly mediated by a reduction in body fat.
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Article Contents Abstract. Conflict of Interest. Author Contributions. Data Availability. Article. Corrected proof. Oxford Academic. Google Scholar. Camille Lassale, PhD. Department of Nutrition, Harvard T. Chan School of Public Health. Julia Warnberg, PhD. Jadwiga Konieczna, PhD. Hana Lancova, PhD. Servicio Navarro de Salud Osasunbidea.
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